NR1I3 and metabolic dysfunction-associated steatotic liver disease: Activation of CAR in mice with 1,4-Bis [2-(3,5-dichloropyridyloxy)] benzene (TCPOBOP) increased serum triglycerides and hepatic fatty acid synthesis and repressed adaptation to hyperlipidemia, which is expected to favor the development of NAFLD (Rezen et al., 2009).