The only exception appears to involve GSTP1 Ile105Val, since three different studies (Zárate et al., 2007; Yao et al., 2010; Zhang et al., 2011), exploring anthracycline-based protocols, suggest higher risk of severe hematological toxicity (neutropenia or leucopenia) for patients with variant genotypes. Here, GSTP1 is linked to Decreased total neutrophil count.