Among US patients who had not previously participated in US HypoCCS (1034 GH-treated and 233 untreated), there were no statistically significant differences in the proportion of GH-treated and untreated patients reporting dyspnea (1.5% vs 0.9%, respectively), sleep apnea (1.6% vs 2.6%), hypertension (3.8% vs 2.1%), or decreased libido (0.2% vs 0%). This evidence concerns the gene GH1 and Hypertension.