PTEN mutations, β-catenin gene mutations or alternative deregulation of these pathways and microsatellite instabilities due to loss of expression of MLH1, MSH2, or other MMR genes have each been reported in up to 20% of endometrioid ovarian carcinomas and are also observed in the closely related endometrioid endometrial cancer [65,66]. Here, MLH1 is linked to ovarian endometrioid carcinoma.