Schaier et al. [35] reported that both the retinoic acid receptor alpha (RARα-specific agonist AGN 195183 and the retinoid X receptor (RXR) specific agonist AGN 194204 reduced the gene expression of glomerular TGF-β1 and prepro-ET1, and alleviated renal damage in rats with established chronic glomerulonephritis (chronic mesangioproliferative Thy-GN (MoAb 1-22-3) rat model). This evidence concerns the gene RARA and ganglioneuroma.