CHUK and leukemia: Different from ROS-induced nuclear IKKα on p53 stability in ROS-treated human MOLT-4 and HL-60 leukemia cells, cisplatin-activated IKKα nuclear translocation did not lead to p53 stabilization in HepG2 cells [53,54], suggesting that IKKα-dependent protein stabilization is cell type- and stimulus-specific.