Figure 1 shows the receiver operating characteristic analysis (ROC) plot for all women with epithelial ovarian cancer and benign diseases, the area under the curve (AUC) for CA125 was 0.82 (95% CI 0.7-0.94) and for HE4 was 0.96 (95% CI 0.9-1.0) (p <0.01) for distinguishing between EOC and benign disease. The gene discussed is WFDC2; the disease is ovarian carcinoma.