In conclusion, on performing an extensive analysis for analyzing the association of the CNDP1/CNDP2 locus with diabetic nephropathy in Japanese subjects with type 2 diabetes, we obtained suggestive evidence that rs12604675-A contributes to susceptibility to overt proteinuria in Japanese women with type 2 diabetes, although the conclusion in this study need to be validated in an independent cohort. This evidence concerns the gene CNDP1 and diabetic kidney disease.