GSTP1 and open-angle glaucoma: As to GSTP1, previous studies did not identify differences between POAG patients and control individuals in the frequencies of GSTP1 Ile 105 Val genotypes [20], [22], [26], [28]; however, by pooled these studies, we found that GSTP1 polymorphism was significantly correlated with increased POAG risk in Caucasian in a recessive model.