GPT and Hepatic fibrosis: These results show that the treatment effect of GA may be due to its ability to promote Nrf2 nuclear transcription and enhance the Nrf2 target genes’ expression, then inducing the MDA content and oxidases (GOT/GPT/MAO) activity decreased, the anti-oxidases (SOD/CAT/GSH-Px) activity increased toward the formation of trichloromethyl radicals that are capable of inducing liver fibrosis.