As shown in Fig 5 we found highly comparable methylation levels (p = n.s.)of LY75, ADORA2A, ERBB3 and HOXB13 CGIs in pre- and post-HTX, indicating that the observed methylation differences in DCM are not due to methylation changes in the controls receiving immunosuppressive medication. This evidence concerns the gene ERBB3 and familial dilated cardiomyopathy.