Nevertheless, after a couple of years acquiring breast cancer families that did not seem to be due to BRCA1, Richard Wooster (then a post doc with me) and the group embarked on another genome-wide search by genetic linkage analysis (in collaboration with David Goldgar and others) and ultimately located BRCA2 in 1994 to chromosome 13q, in the process of course, also proving that the second gene existed (Wooster et al, 1994). The gene discussed is BRCA2; the disease is breast carcinoma.