The re-stimulation with TCR and TLR3 agonist simultaneously induced significantly lower levels of IFN-γ, IL-13, TNF-α, as well as GM-CSF, CCL4 and CCL5, in BD than in HC (P = 0.008, 0.029 and 0.021, 0.018, 0.012 and 0.044, respectively) (Figure 4). Here, CCL4 is linked to Behcet disease.