We performed RT-qPCR analyses on the following eleven genes: Rhodopsin (phototransduction, RP and Congenital stationary night blindness (CSNB)), Gnat1 (phototransduction, CSNB), S-opsin, M-opsin (phototransduction, color blindness), Pde6g (phototransduction, RP), Slc24a1 (phototransduction, CSNB), Rdh12 (visual cycle, LCA and RP), Rpgrip1 (ciliary function, LCA and CORD), Nrl (transcription regulation, RP), Cabp4 (synaptic function, CSNB, LCA), and Fscn2 (Cytoskeleton regulation, RP and macular dystrophy). The gene discussed is NRL; the disease is Macular dystrophy.