Interestingly, the induction of this gene by ER stress was not affected by OASIS knock-down, suggesting that OASIS is not required for Col1a1 induction in glioma cells or that perhaps another ATF6 family isoform is able to compensate for OASIS loss allowing for Col1a1 induction in glioma cells. This evidence concerns the gene CREB3L1 and glioma.