Analysis of The Cancer Genome Atlas (cancergenome.nih.gov/) glioma expression database [40], as well as the GBMBase (http://www.gbmbase.org) which focuses on glioblastoma multiforme research, indicates that OASIS and various ER stress response genes are changed in gliomas relative to control tissue (Supplemental data Table S1 and Figure S1). Here, CREB3L1 is linked to glioma.