ARNT and neoplasm: miR-29 down-regulates MMP2, indirectly reducing VEGFR2 signaling and angiogenesis, miR-107 reduces HIF-1b, with subsequently reduced angiogenesis, tumor growth, and VEGF expression, and miR-125b was shown to inhibit PIGF and VE-cadherin in different cell lines, inhibiting angiogenesis.