In prostate cancer, there is evidence that down-regulation of miR-107 is correlated with up-regulation of the mitogen and growth factor granulin (GRN); other members of this miRNA family have also been shown to display this pattern of down-regulation with associated up-regulation of GRN in 11 different types of cancer (Wang et al., 2010b). The gene discussed is GRN; the disease is prostate cancer.