E2F3 and Alzheimer disease: However, the specific interactions of miR-125b with molecules in a large variety of pathways have not been investigated in AD; research to determine whether miR-125b directly interacts with the molecules listed above including angiogenic VEGF, cell cycle regulatory E2F3, and apoptotic activator BMF could shed more light on the molecular mechanisms involved in AD pathology and further elucidate the pathways involved in this disease.