In cholangiocarcinoma cells miR-29 was transcriptionally repressed by NF-κB protein, a key molecule in the inflammatory pathway, as well as c-Myc and hedgehog proteins, implicating this miRNA in proliferation down-regulation (Pikarsky et al., 2004;Mott et al., 2007). This evidence concerns the gene NFKB1 and cholangiocarcinoma.