In an endometrial cancer cell line, miR-9 was shown to significantly reduce expression of Forkhead box O1 (FOXO1), a transcription factor, while in another endometrial cancer cell line inhibition of this and several other miRNAs resulted in re-expression of FOXO1, cell cycle arrest, and apoptosis (Myatt et al., 2010). This evidence concerns the gene FOXO1 and endometrial cancer.