IL1B and Alzheimer disease: It was shown to function similarly to miR-125b in the AD inflammatory and oxidative stress pathways, as it was shown to be up-regulated by NF-κB in response to IL-1β and Aβ42 or oxidative stress in cultured human neuronal glial cells, and to decrease expression of CFH (Lukiw et al., 2008;Cui et al., 2010;Lukiw and Alexandrov, 2012).