Although NETosis may be viewed as a dangerous form of death based on recent associations with SLE, Wegener’s granulomatosis, and Felty’s syndrome, several antimicrobial proteins that are enriched in NETs (e.g., α-defensins and the cathelicidin LL37; Brinkmann et al., 2004; Lai and Gallo, 2009; Urban et al., 2009), also have anti-inflammatory activities which favor resolution of infection and repair of damaged tissues (reviewed in Lai and Gallo, 2009). The gene discussed is CAMP; the disease is systemic lupus erythematosus.