IFNA1 and systemic lupus erythematosus: In addition, apoptotic material in complex with autoantibodies can induce production of IFN-α by pDCs (Bave et al., 2000, 2001, 2003; Lovgren et al., 2004; Vollmer et al., 2005), a critical cytokine in the current paradigm of SLE (Ronnblom et al., 2011) that is gaining interest in the pathogenic model of SS, autoimmune myositis, scleroderma, and RA (Greenberg et al., 2005; Hjelmervik et al., 2005; Gottenberg et al., 2006; Walsh et al., 2007; Higgs et al., 2011, 2012; van et al., 2011).