IL5 and infection: DNA is rapidly expelled by the eosinophils in response to stimulation with LPS, eotaxin, complement factor 5a (C5a) or infection with Gram-negative bacteria after priming with interleukin 5 (IL-5) or IFN-γ (Figure 1), which, in this case, was shown to be essential for the explosive release of mtDNA by eosinophils.