IGHE and asthma: As for the relationship between IL-22, food-specific IgE and asthma the data in Figure 1 indicated that with respect to the expression of IL-22 in blood samples, significant differences were consistently found between those asthmatic children showing positive IgE reaction toward egg and milk, and the sub-group of non-asthmatic children showing no specific IgE reaction but not those showing positive IgE toward wheat.