In common with their report, we identified genomic amplification of AURKA in MPNST cell-lines (Fig S2B) and found that robust inhibition of growth in vitro followed the silencing of AURKA or the treatment of cells with AKI, which also stabilized the growth of two primary, human MPNST when grown as xenotransplants in animal models. This evidence concerns the gene AURKA and malignant peripheral nerve sheath tumor.