In keeping with these results, the mean rate of Cyclin D1 expression in the papillomas was 8.81% (8.81% ± 8.41%), whereas the mean expression rate of Cyclin D1 in the papillary carcinomas exhibited a statistically significant increase to 27.54% (27.54% ± 15.43%, p < 0.01, Figure 2). The gene discussed is CCND1; the disease is papilloma.