In infection with Listeria, immunity to the bacterium has been shown to be via activation of the BDKRB2 receptor [38] and in infections with Staphylococcus aureus or Pseudomonas aeruginosa, secreted components of the pathogens have been demonstrated to upregulate human BDKRB1 in epithelial cells via NFkB-pathways [39], [40]. This evidence concerns the gene NFKB1 and infection.