As attachment to host epithelial cells is thought to be the crucial step in infection, we began our studies with the identification of cytoadhesive membrane proteins, such as the P80 secretin and the lipoproteins P50/Vaa, P60 and OppA [2], [3], [4], and identified the multifunctional OppA protein as a pathogenic factor of M. hominis. Here, NFKB1 is linked to infection.