AGT and cardiac hypertrophy: A possible pathway by which Ang II may cause myocardial hypertrophy is as follows: Ang II ↑→miR-30a ↓→beclin-1 expression ↑→ excessive autophagy → myocardial hypertrophy.Since myocardial hypertrophy is not a key feature of all stages of cardiac remodeling, this pathway may not apply to all pathophysiological processes that underlie cardiac remodeling.