The association between AMD,PCV and three SNPs in these gene regions, namely rs1061170 (CFH), rs10490924 (ARMS2), and rs11200638 (HTRA1), were verified by a number of research groups in Caucasians and Japanese [33], [36], [37], [38], [39], [40], [41], [42], [43]. This evidence concerns the gene ARMS2 and age-related macular degeneration.