FASLG and cancer: FASL −844 C/T is located in a putative binding motif for a transcription factor, CAAT/enhancer-binding protein h, and the −844 C allele may increase basal expression of FASL compared with the −844 T allele [27], suggesting that the FASL −844 C/T polymorphism may influence FASL expression and FasL mediated signaling, and ultimately, the susceptibility to cancer.