VCAM-1 mediates the adhesion of eosinophils, lymphocytes, monocytes, and basophils to vascular endothelium [55] and has been shown to be upregulated in pancreatic disease [56]; however, its role in mixed IPMN and cancer remains unclear. The gene discussed is VCAM1; the disease is pancreatic intraductal papillary-mucinous neoplasm.