IFNG and type 1 diabetes mellitus: In diabetic mice induced by streptozotocin (STZ), it has been shown that the administration of IL-23 increases IL-17, TNF-α, and IFN-γ secretion, which is associated with the onset of extremely severe T1D, implicating CAMφs in the recruitment, differentiation, and expansion of pathogenic Th17 lymphocytes, contributing to β cell death and T1D induction [48].