MMP9 and ovarian cancer: The mechanism of invasion and migration stimulated by HGF was elusive until recent studies discovered a novel mechanism: HGF activates p70S6k which induces matrix metalloproteinase 9 (MMP9) degradation, a matrix protein which is known to be responsible for promoting cellular inavsion and has been found to be associated with poor prognosis in late stage ovarian cancer patients [45–47].