Therefore, the preoperative correct diagnosis has been difficult; however, recent advances in imaging diagnosis through a combination of ultrasonography (US), computed tomography (CT), magnetic resonance imaging (MRI), and angiography and specific immunohistochemical analysis of this tumor using human melanoma black-45 antigen (HMB-45) staining have resulted in accurate diagnosis and it is reported that the current accurate preoperative diagnosis was made in 25%–52% of cases [8, 9]. Here, PMEL is linked to neoplasm.