However, the associations of DRB1*15∶01 (Pc = 0.3450, OR 2.93, 95%CI 1.34–6.42), DQB1*06∶02 (Pc = 0.1848, OR 2.93, 95%CI 1.34–6.42), or DPB1*05∶01 (Pc = 0.0941, OR 2.16, 95%CI 1.26–3.70) with anti-La/SS-A antibodies did not reach statistical significance after excluding RA patients with secondary SS, because of reduced sample numbers after the exclusion. The gene discussed is HLA-DRB1; the disease is rheumatoid arthritis.