ZNF217 and ovarian cancer: Previous studies to determine the function of Zinc-finger protein 217 (ZNF217) using Affymetrix Gene Chip analysis in the ovarian cancer cell line, HO-8910, with HG-U133 plus 2.0 arrays demonstrated that silencing of the ZNF217 gene resulted in downregulation (approximately 8-fold) of 164 genes compared to normal cells.