CBFA2T3 and acute myeloid leukemia: ETO2, a member of the highly conserved ETO family of transcriptional corepressors (ETO/MTG8, ETO2/MTG16, and MTGR1; Davis et al., 2003), was originally identified through its involvement in a translocation breakpoint associated with acute myeloid leukemia (Gamou et al., 1998).