The development of accelerated atherosclerosis and typical for CKD calcification of tunica media, labeled as Monckeberg’s sclerosis is associated with transformation of vascular smooth muscle cells (VSMCs) into osteoblast-like cells, able to synthesize bone matrix protein-2 (BMP-2), matrix Gla protein (MGP) and osteopontin [3]. This evidence concerns the gene MGP and atherosclerosis.