MGP and hypertensive disorder: In patients with CAC, CACS was significantly associated with the HD vintage (R = 0.27, p = 0.02), pack-years of smoking (R = 0.37, p = 0.002), duration of hypertension therapy (R = 0.28, p = 0.03), plasma levels of osteoprotegerin (R = 0.32, p = 0.01) and MGP (R = 0.305, p = 0.03).