TP53 and breast carcinoma: For patients with inactive p53 and those with intact p53 breast cancer, the DFS rates were 46.1% and 83.6% respectively (P = 0.0007, HR 5.15, 95% C.I.: 1.99–13.33), and OAS rates were 57.1% and 86.7% respectively (P = 0.0029, HR 4.81, 95% C.I.: 1.71–13.52) (Table 4).