VEGFA and acute myocardial infarction: The importance of scar prevascularization to the presently described in situ cellular reprogramming strategy is supported by our observation of the ability of AdVEGF to induce scar vascularization in the setting of the acute myocardial infarction model used in the current study, together with our observation of significant improvements in EF when VEGF was administered as a supplement to GMT compared with the administration of GMT without VEGF.