FBLN1 and Myocardial fibrosis: The idea that fibulin-1 may reflect accumulation of ECM in fibrotic myocardium and correlations found in the present study fit with a recent Brazilian study demonstrating that myocardial fibrosis is a prognostic marker for postoperative outcome.3,4 The main constituents of the myocardial matrix are type I and, to a lesser extent, type III collagen.