APOB and hyperlipidemia: Altered fatty acid metabolism in adipose tissue could lead to elevated circulating fatty acid levels and thereby cause atherogenic hyperlipidemia.1–3 Fatty acids stimulate apolipoprotein B (apoB) synthesis by the liver4 and thereby influence the circulating levels of triglycerides and small, dense low‐density lipoprotein particles.5 Elevation of circulating apoB (hyperapobetalipoproteinemia [or hyperapoB]) and triglycerides is a common atherogenic profile.4–5