The area of myocardial fibrosis in noninfarctedheart was significantly smaller in IL-17A-KO (0.65±0.22%,n=11) and IL-23-KO (0.70±0.18%, n=9) mice than in WTmice (1.72±0.27%, n=10) (Figure 4E and 4F). This evidence concerns the gene IL23A and Myocardial fibrosis.