Two recent articles demonstrated that IL-17A is involved in the early cardiomyocytedeath evident in ischemia–reperfusion injury, with functional involvementdemonstrated 2 to 3 hours after reperfusion.22,23 Here, we createda substantially sized MI by permanent ligation of the coronary artery, andidentified a functional link between the IL-23/IL-17A signaling axis andγδT cells in late-stage LV remodeling after MI. Here, IL23A is linked to myocardial infarction.