APOB and diabetes mellitus: Recently, overproduction of remnant lipoproteins has been shown to contribute to dyslipidemia in subjects with type 2 diabetes mellitus,8 and animal studies implicate involvement of several mechanistic pathways.25,26 Data from our lymph cannulation studies (Figure 3 and Table 1) confirm that the influence of MetS can increase the rate of secretion and elevate the triglyceride and cholesterol–to–apoB48 ratio.