In another study in Mynamar, the TNFPD allele haplotype (−238G; −308G; −857T, rs1799724; −1031T, rs1799964) was associated with increased susceptibility to cerebral malaria because the transcription factor OCT-1 binds to TNF −857T in the TNFPD allele but not to TNF −857C in the TNFPA, B and C alleles and interacts with the proinflammatory NF-κB subunit transcription factor p65 at the adjacent binding site [114]. Here, TNF is linked to cerebral malaria.