However, a recent study that assesses the influence of 11 polymorphism in IL4 gene on predisposition to malaria in Mali found a genetic association between IL4 VNTR (rs8179190) and others IL4 mutations (−33C/T; rs2243267; rs2243268; rs2243282) with severe disease, supporting the view that IL4 genetic alterations could be a risk factor for malaria severity [129]. Here, IL4 is linked to malaria.