However, it must be noted that there is a plethora of evidence of expression of NTs and Trks in non-neuronal cells (e.g., Funakoshi et al., 1993; Elkabes et al., 1998; Nemoto et al., 1998; Noga et al., 2002; Hess et al., 2007), although much of this is in the context of cancer (e.g., Tacconelli et al., 2005; Howe et al., 2011; Jin et al., 2011). This evidence concerns the gene NTS and cancer.