Further, autonomic dysreflexia (AD), a life-threatening condition that is common for those living long-term with cervical or high thoracic SCI, is triggered most frequently by nociceptive sensory input (Maiorov et al., 1998; Krassioukov and Fehlings, 1999; Garstang and Miller-Smith, 2007), and sprouting of central terminals of nociceptive neurons, purportedly modulated by NGF, is proposed as a mechanism contributing to AD (Weaver et al., 1997; Krenz et al., 1999; Marsh et al., 2002; Cameron et al., 2006; Ackery et al., 2007). The gene discussed is NGF; the disease is Alzheimer disease.