The levels of circulating proinflammatory cytokines and chemokines such as tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), and monocyte chemoattractant protein-1 (MCP-1) are commonly used as markers of inflammation, and they have been shown to be increased in diabetes [8–10]. This evidence concerns the gene TNF and diabetes mellitus.