GFI1 and chronic myelogenous leukemia, BCR-ABL1 positive: While Gfi1 was shown to be over-expressed in chronic myeloid leukemias in a case study in China [19], a variant of Gfi1 (S36N) (in which the serine residue at position 36 is replaced by an asparagine) was observed to be prevalent in AML patients in Europe [20].