In rats, however, although the TRPV1 agonist capsaicin induced similar hypertension as anandamide or methanandamide, only the non-selective TRPV blocker ruthenium red but not the TRPV1 antagonist capsazepine was able to inhibit the pressor response to anandamide [34], [61]. Here, TRPV1 is linked to hypertensive disorder.