Cystatin SA III precursor (spot ID 10), lacrimal lipocalin precursor (spot ID 24) and lacritin precursor (spot ID 30) were down regulated, while alpha 1 antitrypsin (spot ID 63), apolipoprotein (spot ID 32), haptoglobin (spot ID 18 & 19), albumin (spot ID 58), zinc α 2 glycoprotein (ZAG) (spot ID 38), lactoferrin (spot ID 52), were up regulated in the keratitis tear compared to control tear (Table 4 & Figure 8). This evidence concerns the gene HP and keratitis.