BMI1 and cancer: The average score for the staining intensity of BMI1 in stroma of normal tissues was 0.81±0.07 (n = 70), and was significantly lower than high-grade stage II (1.8±0.08; n = 36), stage III (2.26±0.10 n = 28) and stage IV (2.8±0.11; n = 6) cancer specimens (Fig. 1Bii; p<0.05).