BECN1 and cardiac hypertrophy: In the absence of autophagy, the extent of regression of cardiac hypertrophy was attenuated, as indicated by the significant reduction in LVW/BW after DeTAC in control mice, but not in beclin1+/− mice and the decreased % regression of cardiac hypertrophy (which is the percentage decrease in LVW/BW values after 1W DeTAC compared to after 1W TAC alone) (Supplemental Fig. S4) in beclin1+/− mice.