DYX1C1 (dyslexia susceptibility 1 candidate 1; MIM 608706) was identified in a study of a family with a structural chromosomal rearrangement, t(2;15; q11;q21), that segregated with mild intellectual impairment and/or dyslexia (Nopola-Hemmi et al., 2000). The gene discussed is DNAAF4; the disease is Cognitive impairment.