This study found that the same three-marker haplotype in KIAA0319 and the minor allele of SNP rs2143340 that was associated with dyslexia and reduced expression (Paracchini et al., 2008) was also associated with poorer reading and spelling performance in an unselected population and the results were strengthened by adjustment for IQ. Here, KIAA0319 is linked to dyslexia.