α‐Synuclein (α‐syn) is a 140‐residue peptide that assembles to form amyloid‐like fibrils that are deposited in Lewy bodies in Parkinson’s disease.3 α‐Syn fibrils assembled in vitro have been confirmed to have a β‐sheet‐rich structure consistent with the amyloid cross‐β architecture.7 Solid‐state NMR studies on the cross‐β amyloid core of recombinant human α‐syn fibrils have indicated sets of β‐strands at discrete positions between 30–110.8 We have explored the assembly potential and structure of a segment of α‐syn corresponding to positions 37–44 (NH2‐VLYVGSKT‐COOH) herein referred to αSβ1. This evidence concerns the gene ASB1 and Parkinson disease.