Consistent with the hypothesis that cancer cachexia specifically disrupts the efficient mobilization and/or shift from intra-hepatic to serum TG pools, C26 mice showed significantly decreased hepatic VLDL secretion as compared with non-tumour-bearing littermates (Fig 2A), while hepatic ApoB uptake capacity from the serum was slightly impaired (Fig 2B). This evidence concerns the gene APOB and neoplasm.